Next-Generation Sequencing of Mycobacterium tuberculosis.
نویسندگان
چکیده
Technical Appendix Figure. Whole-genome, short-sequencing reads of Mycobacterium tuberculosis strain 4542 mapped to complete genome of reference strain H37Rv (NC_00962.3) by using Geneious 9.0 package: genome locus of spacers 7–9 in DR/CRISPR locus. Spacer numbers are given according to 43-spoligotyping (1). DR/CRISPR locus in M. tuberculosis is located on complementary strand, whereas spacers are consecutively numbered within the locus, not genome. Such a situation (IS6110 asymmetrically inserted in the direct repeat unit immediately adjacent to a spacer) was discovered by Filliol et al. (2).
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عنوان ژورنال:
- Emerging infectious diseases
دوره 22 6 شماره
صفحات -
تاریخ انتشار 2016